Cargando…

Fyn Mediates High Glucose-Induced Actin Cytoskeleton Reorganization of Podocytes via Promoting ROCK Activation In Vitro

Fyn, a member of the Src family of tyrosine kinases, is a key regulator in cytoskeletal remodeling in a variety of cell types. Recent studies have demonstrated that Fyn is responsible for nephrin tyrosine phosphorylation, which will result in polymerization of actin filaments and podocyte damage. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lv, Zhimei, Hu, Mengsi, Ren, Xiaoxu, Fan, Minghua, Zhen, Junhui, Chen, Liqun, Lin, Jiangong, Ding, Nannan, Wang, Qun, Wang, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736797/ https://www.ncbi.nlm.nih.gov/pubmed/26881253 http://dx.doi.org/10.1155/2016/5671803

Ejemplares similares

FAK contributes to proteinuria in hypercholesterolaemic rats and modulates podocyte F‐actin re‐organization via activating p38 in response to ox‐LDL
por: Hu, Mengsi, et al.
Publicado: (2016)

LncRNA MALAT1 is dysregulated in diabetic nephropathy and involved in high glucose‐induced podocyte injury via its interplay with β‐catenin
por: Hu, Mengsi, et al.
Publicado: (2017)

Podocyte-specific Rac1 deficiency ameliorates podocyte damage and proteinuria in STZ-induced diabetic nephropathy in mice
por: Lv, Zhimei, et al.
Publicado: (2018)

Regulation of the Actin Cytoskeleton in Podocytes
por: Blaine, Judith, et al.
Publicado: (2020)

Dynamic reorganization of the actin cytoskeleton
por: Letort, Gaëlle, et al.
Publicado: (2015)

Fyn‐binding protein ADAP supports actin organization in podocytes
por: Wu, Zhenzhen, et al.
Publicado: (2017)

TRPV2 interacts with actin and reorganizes submembranous actin cytoskeleton
por: Yadav, Manoj, et al.
Publicado: (2020)

Levamisole Modulation of Podocytes’ Actin Cytoskeleton in Nephrotic Syndrome
por: Veissi, Susan T., et al.
Publicado: (2023)

Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy
por: Wang, Ziyang, et al.
Publicado: (2022)

Myo1e Impairment Results in Actin Reorganization, Podocyte Dysfunction, and Proteinuria in Zebrafish and Cultured Podocytes
por: Mao, Jianhua, et al.
Publicado: (2013)

Influence of ROCK Pathway Manipulation on the Actin Cytoskeleton Height
por: Grandy, Carolin, et al.
Publicado: (2022)

F-actin cytoskeleton reorganization is associated with hepatic stellate cell activation
por: CUI, XIAODONG, et al.
Publicado: (2014)

Role of Actin Cytoskeleton Reorganization in Polarized Secretory Traffic at the Immunological Synapse
por: Calvo, Victor, et al.
Publicado: (2021)

Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell Spread
por: El Najjar, Farah, et al.
Publicado: (2016)

Renal Lipotoxicity-Associated Inflammation and Insulin Resistance Affects Actin Cytoskeleton Organization in Podocytes
por: Martínez-García, Cristina, et al.
Publicado: (2015)

Mycophenolic acid directly protects podocytes by preserving the actin cytoskeleton and increasing cell survival
por: Abo Zed, Seif El Din, et al.
Publicado: (2023)

Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis
por: Uetaki, Megumi, et al.
Publicado: (2022)

The podocyte cytoskeleton in health and in disease
por: Mathieson, Peter W.
Publicado: (2012)

Calcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapies
por: Wieder, Nicolas, et al.
Publicado: (2015)

ARHGEF4-mediates the actin cytoskeleton reorganization of hepatic stellate cells in 3-dimensional collagen matrices
por: Zhang, Xiaowei, et al.
Publicado: (2019)

Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells
por: Villalba, Martin, et al.
Publicado: (2001)

Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton
por: Kumar, Vinod, et al.
Publicado: (2019)

Reorganization of the nuclear lamina and cytoskeleton in adipogenesis
por: Verstraeten, Valerie L. R. M., et al.
Publicado: (2011)

Myeloperoxidase modulates human platelet aggregation via actin cytoskeleton reorganization and store-operated calcium entry
por: Gorudko, Irina V., et al.
Publicado: (2013)

FAM40A alters the cytoskeleton of podocytes in familial focal and segmental glomerulosclerosis by regulating F-actin and nephrin
por: Chen, Zhou, et al.
Publicado: (2018)

Dissecting the Mechanisms of Doxorubicin and Oxidative Stress-Induced Cytotoxicity: The Involvement of Actin Cytoskeleton and ROCK1
por: Wei, Lei, et al.
Publicado: (2015)

Jak3 Enables Chemokine-Dependent Actin Cytoskeleton Reorganization by Regulating Cofilin and Rac/Rhoa GTPases Activation
por: Ambriz-Peña, Xochitl, et al.
Publicado: (2014)

HIF-1α activation results in actin cytoskeleton reorganization and modulation of Rac-1 signaling in endothelial cells
por: Weidemann, Alexander, et al.
Publicado: (2013)

Taking control: reorganization of the host cytoskeleton by Chlamydia
por: Wesolowski, Jordan, et al.
Publicado: (2017)

0.5-Gy X-ray irradiation induces reorganization of cytoskeleton and differentiation of osteoblasts
por: Huang, Qun, et al.
Publicado: (2021)

Role of Transient Receptor Potential Canonical Channel 6 (TRPC6) in Diabetic Kidney Disease by Regulating Podocyte Actin Cytoskeleton Rearrangement
por: Wang, Qian, et al.
Publicado: (2020)

Actin cytoskeleton in angiogenesis
por: Yadunandanan Nair, Nidhi, et al.
Publicado: (2022)

Disrupting actin filaments enhances glucose-stimulated insulin secretion independent of the cortical actin cytoskeleton
por: Polino, Alexander J., et al.
Publicado: (2023)

Disrupting actin filaments enhances glucose-stimulated insulin secretion independent of the cortical actin cytoskeleton
por: Polino, Alexander J., et al.
Publicado: (2023)

The Non-Catalytic Carboxyl-Terminal Domain of ARFGAP1 Regulates Actin Cytoskeleton Reorganization by Antagonizing the Activation of Rac1
por: Siu, Ka Yu, et al.
Publicado: (2011)

ELMO proteins transduce G protein-coupled receptor signal to control reorganization of actin cytoskeleton in chemotaxis of eukaryotic cells
por: Xu, Xuehua, et al.
Publicado: (2017)

Low-dose X-ray irradiation induces morphological changes and cytoskeleton reorganization in osteoblasts
por: Huang, Qun, et al.
Publicado: (2020)

Dasatinib inhibits actin fiber reorganization and promotes endothelial cell permeability through RhoA‐ROCK pathway
por: Dasgupta, Swapan K., et al.
Publicado: (2017)

RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signal
por: Huang, Zongshun, et al.
Publicado: (2016)

The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton
por: Rogg, M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ab2vboila29dbdtma0aatdjcdt