Structures of the troponin core domain containing the cardiomyopathy-causing mutants studied by small-angle X-ray scattering

Troponin (Tn), consisting of three subunits, TnC, TnI, and TnT, is a protein in the thin filaments in muscle, and, together with another thin-filament protein tropomyosin (Tm), plays a major role in regulation of muscle contraction. Various mutations of Tn cause familial hypertrophic cardiomyopathy....

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Detalles Bibliográficos
Autores principales: Matsuo, Tatsuhito, Takeda, Soichi, Oda, Toshiro, Fujiwara, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2015
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736830/
https://www.ncbi.nlm.nih.gov/pubmed/27493864
http://dx.doi.org/10.2142/biophysico.12.0_145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736830/
https://www.ncbi.nlm.nih.gov/pubmed/27493864
http://dx.doi.org/10.2142/biophysico.12.0_145

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