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Structures of the troponin core domain containing the cardiomyopathy-causing mutants studied by small-angle X-ray scattering
Troponin (Tn), consisting of three subunits, TnC, TnI, and TnT, is a protein in the thin filaments in muscle, and, together with another thin-filament protein tropomyosin (Tm), plays a major role in regulation of muscle contraction. Various mutations of Tn cause familial hypertrophic cardiomyopathy....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society of Japan (BSJ)
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736830/ https://www.ncbi.nlm.nih.gov/pubmed/27493864 http://dx.doi.org/10.2142/biophysico.12.0_145 |