Cargando…

Hypochlorite-Modified Albumin Upregulates ICAM-1 Expression via a MAPK–NF-κB Signaling Cascade: Protective Effects of Apocynin

Hypochlorite-modified albumin (HOCl-alb) has been linked to endothelial dysfunction, which plays an important role in the development of hypertension, diabetes, and chronic kidney disease. However, whether HOCl-alb induces endothelial dysfunction via vascular inflammation and whether a signaling pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Dong-dong, Niu, Hong-xin, Peng, Fen-fen, Long, Hai-bo, Liu, Zong-rui, Zhao, Hao, Chen, Yi-hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736979/ https://www.ncbi.nlm.nih.gov/pubmed/26881015 http://dx.doi.org/10.1155/2016/1852340

Ejemplares similares

Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state
por: Trevelin, Silvia Cellone, et al.
Publicado: (2016)

VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway
por: Zhang, Meiying, et al.
Publicado: (2022)

Blockade of NF-κB and MAPK pathways by ulinastatin attenuates wear particle-stimulated osteoclast differentiation in vitro and in vivo
por: Ru, Jiang-Ying, et al.
Publicado: (2016)

Improvement of Pharmacokinetics Behavior of Apocynin by Nitrone Derivatization: Comparative Pharmacokinetics of Nitrone-Apocynin and its Parent Apocynin in Rats
por: Wang, Kaiyu, et al.
Publicado: (2013)

Apocynin: Molecular Aptitudes
por: Stefanska, J., et al.
Publicado: (2008)

Degraded Carrageenan Causing Colitis in Rats Induces TNF Secretion and ICAM-1 Upregulation in Monocytes through NF-κB Activation
por: Benard, Claudine, et al.
Publicado: (2010)

Transcriptional upregulation of MAPK15 by NF-κB signaling boosts the efficacy of combination therapy with cisplatin and TNF-α
por: Wu, Dan-Dan, et al.
Publicado: (2022)

Resveratrol prevents TNF-α-induced VCAM-1 and ICAM-1 upregulation in endothelial progenitor cells via reduction of NF-κB activation
por: Zhang, Yefei, et al.
Publicado: (2020)

Sphingosine 1-Phosphate-Induced ICAM-1 Expression via NADPH Oxidase/ROS-Dependent NF-κB Cascade on Human Pulmonary Alveolar Epithelial Cells
por: Lin, Chih-Chung, et al.
Publicado: (2016)

Leptin Promotes cPLA(2) Gene Expression through Activation of the MAPK/NF-κB/p300 Cascade
por: Hsu, Pei-Sung, et al.
Publicado: (2015)

Haloperidol Instigates Endometrial Carcinogenesis and Cancer Progression by the NF-κB/CSF-1 Signaling Cascade
por: Chiang, Jung-Ying, et al.
Publicado: (2022)

Association between NF-κB Pathway Gene Variants and sICAM1 Levels in Taiwanese
por: Wu, Semon, et al.
Publicado: (2017)

The UII/UT System Mediates Upregulation of Proinflammatory Cytokines through p38 MAPK and NF-κB Pathways in LPS-Stimulated Kupffer Cells
por: Liu, Liang Ming, et al.
Publicado: (2015)

Resveratrol mitigates lipopolysaccharide-mediated acute inflammation in rats by inhibiting the TLR4/NF-κBp65/MAPKs signaling cascade
por: Wang, Guangxi, et al.
Publicado: (2017)

Resveratrol inhibits LPS-induced inflammation through suppressing the signaling cascades of TLR4-NF-κB/MAPKs/IRF3
por: Tong, Wenzhi, et al.
Publicado: (2020)

Blockage of NOX2/MAPK/NF-κB Pathway Protects Photoreceptors against Glucose Deprivation-Induced Cell Death
por: Fan, Bin, et al.
Publicado: (2017)

Theaflavin Inhibits LPS-Induced IL-6, MCP-1, and ICAM-1 Expression in Bone Marrow-Derived Macrophages Through the Blockade of NF-κB and MAPK Signaling Pathways
por: Kim, Seewan, et al.
Publicado: (2011)

Apocynin promotes neural function recovery and suppresses neuronal apoptosis by inhibiting Tlr4/NF-κB signaling pathway in a rat model of cerebral infarction
por: Pan, Lemen, et al.
Publicado: (2018)

Artemisia gmelinii Attenuates Lung Inflammation by Suppressing the NF-κB/MAPK Pathway
por: Kim, Seung Yong, et al.
Publicado: (2022)

Inhibiting USP14 ameliorates inflammatory responses in trophoblast cells by suppressing MAPK/NF‐κB signaling
por: Zhao, Yingzi, et al.
Publicado: (2021)

2-Phenylnaphthalene Derivatives Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Mediators by Downregulating of MAPK/NF-κB Pathways in RAW 264.7 Macrophage Cells
por: Chang, Chi-Fen, et al.
Publicado: (2017)

Endothelial MAPKs Direct ICAM-1 Signaling to Divergent Inflammatory Functions
por: Dragoni, Silvia, et al.
Publicado: (2017)

Cerevisterol Alleviates Inflammation via Suppression of MAPK/NF-κB/AP-1 and Activation of the Nrf2/HO-1 Signaling Cascade
por: Alam, Md Badrul, et al.
Publicado: (2020)

Rosmarinic Acid Attenuates the Lipopolysaccharide-Provoked Inflammatory Response of Vascular Smooth Muscle Cell via Inhibition of MAPK/NF-κB Cascade
por: Chen, Ching-Pei, et al.
Publicado: (2022)

Malting barley carbon dots-mediated oxidative stress promotes insulin resistance in mice via NF-κB pathway and MAPK cascade
por: Zhang, Boya, et al.
Publicado: (2022)

Upregulation of ICAM-1 in diabetic rats after transient forebrain ischemia and reperfusion injury
por: Jing, Li, et al.
Publicado: (2014)

Inhibition of NADPH Oxidase by Apocynin Attenuates Progression of Atherosclerosis
por: Kinkade, Kara, et al.
Publicado: (2013)

The Importance of Myeloperoxidase in Apocynin-Mediated NADPH Oxidase Inhibition
por: de Almeida, Ana Carolina, et al.
Publicado: (2012)

Apocynin attenuates left ventricular remodeling in diabetic rabbits
por: Qiu, Jiuchun, et al.
Publicado: (2017)

Apocynin Dietary Supplementation Delays Mouse Ovarian Ageing
por: Timóteo-Ferreira, F., et al.
Publicado: (2019)

Hemokinin-1 Gene Expression Is Upregulated in Microglia Activated by Lipopolysaccharide through NF-κB and p38 MAPK Signaling Pathways
por: Sakai, Atsushi, et al.
Publicado: (2012)

Endothelial lipase is upregulated by interleukin-6 partly via the p38 MAPK and p65 NF-κB signaling pathways
por: Yue, Xin, et al.
Publicado: (2016)

Lactobacillus brevis 23017 Relieves Mercury Toxicity in the Colon by Modulation of Oxidative Stress and Inflammation Through the Interplay of MAPK and NF-κB Signaling Cascades
por: Jiang, Xinpeng, et al.
Publicado: (2018)

Attenuation of Inflammatory Symptoms by Icariside B2 in Carrageenan and LPS-Induced Inflammation Models via Regulation of MAPK/NF-κB Signaling Cascades
por: Alam, Md Badrul, et al.
Publicado: (2020)

Apocynin and Diphenyleneiodonium Induce Oxidative Stress and Modulate PI3K/Akt and MAPK/Erk Activity in Mouse Embryonic Stem Cells
por: Kučera, Jan, et al.
Publicado: (2016)

PRMT5 inhibition attenuates cartilage degradation by reducing MAPK and NF-κB signaling
por: Dong, Yonghui, et al.
Publicado: (2020)

AST-120 Improves Cardiac Dysfunction in Acute Kidney Injury Mice via Suppression of Apoptosis and Proinflammatory NF-κB/ICAM-1 Signaling
por: Shen, Wen-Ching, et al.
Publicado: (2021)

Agonistic anti-ICAM-1 antibodies in scleroderma: Activation of endothelial pro-inflammatory cascades
por: Wolf, Sabine I., et al.
Publicado: (2013)

Neuroprotective mechanism of salvianolic acid B against cerebral ischemia–reperfusion injury in mice through downregulation of TLR4, p‐p38MAPK, p‐JNK, NF‐κB, and IL‐1β
por: Zheng, Xiu‐fen, et al.
Publicado: (2023)

Inhibition of miR-101-3p protects against sepsis-induced myocardial injury by inhibiting MAPK and NF-κB pathway activation via the upregulation of DUSP1
por: Xin, Ye, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4ie04c7a77slr3q9aovtve6mo5