Cargando…
mGlu5 Receptors and Relapse to Cocaine-Seeking: The Role of Receptor Trafficking in Postrelapse Extinction Learning Deficits
We have previously demonstrated that MTEP, an allosteric antagonist of mGlu5, infused into the nucleus accumbens attenuates relapse after abstinence from cocaine self-administration. MTEP infused into the dorsolateral striatum (dlSTR) does not alter relapse but has long-lasting effects on subsequent...
Autores principales: | Knackstedt, Lori A., Schwendt, Marek |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736983/ https://www.ncbi.nlm.nih.gov/pubmed/26881139 http://dx.doi.org/10.1155/2016/9312508 |
Ejemplares similares
-
A novel rat model of comorbid PTSD and addiction reveals intersections between stress susceptibility and enhanced cocaine seeking with a role for mGlu5 receptors
por: Schwendt, Marek, et al.
Publicado: (2018) -
Extinction vs. Abstinence: A Review of the Molecular and Circuit Consequences of Different Post-Cocaine Experiences
por: Schwendt, Marek, et al.
Publicado: (2021) -
The roles of rat medial prefrontal and orbitofrontal cortices in relapse to cocaine-seeking: A comparison across methods for identifying neurocircuits
por: Mesa, Javier R., et al.
Publicado: (2022) -
Allosteric Modulators for mGlu Receptors
por: Gasparini, F, et al.
Publicado: (2007) -
mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists
por: Zammataro, Magda, et al.
Publicado: (2011)