Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges

Stress urinary incontinence (SUI) is a common urinary system disease that mostly affects women. Current treatments still do not solve the critical problem of urethral sphincter dysfunction. In recent years, there have been major developments in techniques to obtain, culture, and characterize autolog...

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Detalles Bibliográficos
Autores principales: Zhou, Shukui, Zhang, Kaile, Atala, Anthony, Khoury, Oula, Murphy, Sean V., Zhao, Weixin, Fu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737006/
https://www.ncbi.nlm.nih.gov/pubmed/26880983
http://dx.doi.org/10.1155/2016/7060975
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author Zhou, Shukui
Zhang, Kaile
Atala, Anthony
Khoury, Oula
Murphy, Sean V.
Zhao, Weixin
Fu, Qiang
author_facet Zhou, Shukui
Zhang, Kaile
Atala, Anthony
Khoury, Oula
Murphy, Sean V.
Zhao, Weixin
Fu, Qiang
author_sort Zhou, Shukui
collection PubMed
description Stress urinary incontinence (SUI) is a common urinary system disease that mostly affects women. Current treatments still do not solve the critical problem of urethral sphincter dysfunction. In recent years, there have been major developments in techniques to obtain, culture, and characterize autologous stem cells as well as many studies describing their applications for the treatment of SUI. In this paper, we review recent publications and clinical trials investigating the applications of several stem cell types as potential treatments for SUI and the underlying challenges of such therapy.
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spelling pubmed-47370062016-02-15 Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges Zhou, Shukui Zhang, Kaile Atala, Anthony Khoury, Oula Murphy, Sean V. Zhao, Weixin Fu, Qiang Stem Cells Int Review Article Stress urinary incontinence (SUI) is a common urinary system disease that mostly affects women. Current treatments still do not solve the critical problem of urethral sphincter dysfunction. In recent years, there have been major developments in techniques to obtain, culture, and characterize autologous stem cells as well as many studies describing their applications for the treatment of SUI. In this paper, we review recent publications and clinical trials investigating the applications of several stem cell types as potential treatments for SUI and the underlying challenges of such therapy. Hindawi Publishing Corporation 2016 2016-01-10 /pmc/articles/PMC4737006/ /pubmed/26880983 http://dx.doi.org/10.1155/2016/7060975 Text en Copyright © 2016 Shukui Zhou et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Zhou, Shukui
Zhang, Kaile
Atala, Anthony
Khoury, Oula
Murphy, Sean V.
Zhao, Weixin
Fu, Qiang
Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges
title Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges
title_full Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges
title_fullStr Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges
title_full_unstemmed Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges
title_short Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges
title_sort stem cell therapy for treatment of stress urinary incontinence: the current status and challenges
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737006/
https://www.ncbi.nlm.nih.gov/pubmed/26880983
http://dx.doi.org/10.1155/2016/7060975
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