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Characterization of neopeptides in equine articular cartilage degradation

Osteoarthritis is characterized by a loss of extracellular matrix that leads to cartilage degradation and joint space narrowing. Specific proteases, including the aggrecanases ADAMTS‐4 and matrix metalloproteinase 3, are important in initiating and promoting cartilage degradation in osteoarthritis....

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Detalles Bibliográficos
Autores principales: Peffers, Mandy Jayne, Thornton, David James, Clegg, Peter David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737130/
https://www.ncbi.nlm.nih.gov/pubmed/26124002
http://dx.doi.org/10.1002/jor.22963