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Stability of blocked replication forks in vivo

Replication of chromosomal DNA must be carried out to completion in order for a cell to proliferate. However, replication forks can stall during this process for a variety of reasons, including nucleoprotein ‘roadblocks’ and DNA lesions. In these circumstances the replisome copying the DNA may disen...

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Detalles Bibliográficos
Autores principales: Mettrick, Karla A., Grainge, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737137/
https://www.ncbi.nlm.nih.gov/pubmed/26490956
http://dx.doi.org/10.1093/nar/gkv1079