Cargando…

Recombinational repair of radiation-induced double-strand breaks occurs in the absence of extensive resection

Recombinational repair provides accurate chromosomal restitution after double-strand break (DSB) induction. While all DSB recombination repair models include 5′-3′ resection, there are no studies that directly assess the resection needed for repair between sister chromatids in G-2 arrested cells of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Westmoreland, James W., Resnick, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737140/ https://www.ncbi.nlm.nih.gov/pubmed/26503252 http://dx.doi.org/10.1093/nar/gkv1109

Ejemplares similares

PP4 phosphatase cooperates in recombinational DNA repair by enhancing double-strand break end resection
por: Villoria, María Teresa, et al.
Publicado: (2019)

Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation
por: Groth, Petra, et al.
Publicado: (2012)

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks
por: Bolderson, Emma, et al.
Publicado: (2010)

CTCF cooperates with CtIP to drive homologous recombination repair of double-strand breaks
por: Hwang, Soon Young, et al.
Publicado: (2019)

Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair
por: Kalasova, Ilona, et al.
Publicado: (2020)

Direct observation of end resection by RecBCD during double-stranded DNA break repair in vivo
por: Wiktor, Jakub, et al.
Publicado: (2018)

PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks
por: Alonso-de Vega, Ignacio, et al.
Publicado: (2020)

Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination
por: Muñoz-Galván, Sandra, et al.
Publicado: (2013)

Homologous recombination repair intermediates promote efficient de novo telomere addition at DNA double-strand breaks
por: Davé, Anoushka, et al.
Publicado: (2020)

Dna2 initiates resection at clean DNA double-strand breaks
por: Paudyal, Sharad C., et al.
Publicado: (2017)

Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase
por: Köcher, Sabrina, et al.
Publicado: (2012)

Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice
por: Jimeno, Sonia, et al.
Publicado: (2015)

Hedgehog signaling enables repair of ribosomal DNA double-strand breaks
por: Lama-Sherpa, Tshering D, et al.
Publicado: (2020)

Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks
por: Vriend, Lianne E.M., et al.
Publicado: (2016)

RBM6 splicing factor promotes homologous recombination repair of double-strand breaks and modulates sensitivity to chemotherapeutic drugs
por: Machour, Feras E, et al.
Publicado: (2021)

Mechanistic analysis of Xenopus EXO1's function in 5′-strand resection at DNA double-strand breaks
por: Liao, Shuren, et al.
Publicado: (2011)

Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin
por: Bauerschmidt, Christina, et al.
Publicado: (2010)

Transcription-associated recombination is independent of XRCC2 and mechanistically separate from homology-directed DNA double-strand break repair
por: Savolainen, Linda, et al.
Publicado: (2009)

Evidence that MEK1 positively promotes interhomologue double-strand break repair
por: Terentyev, Yaroslav, et al.
Publicado: (2010)

A moonlighting metabolic protein influences repair at DNA double-stranded breaks
por: Torres-Machorro, Ana Lilia, et al.
Publicado: (2015)

Smarcal1 promotes double-strand-break repair by nonhomologous end-joining
por: Keka, Islam Shamima, et al.
Publicado: (2015)

The COP9 signalosome is vital for timely repair of DNA double-strand breaks
por: Meir, Michal, et al.
Publicado: (2015)

GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination
por: Takizawa, Yoshimasa, et al.
Publicado: (2010)

The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks
por: Ngo, Greg H.P., et al.
Publicado: (2015)

Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing
por: Paliwal, Shreya, et al.
Publicado: (2014)

Acetylation of 53BP1 dictates the DNA double strand break repair pathway
por: Guo, Xiang, et al.
Publicado: (2018)

Mechanism of efficient double-strand break repair by a long non-coding RNA
por: Thapar, Roopa, et al.
Publicado: (2020)

DNA polymerase θ-mediated repair of high LET radiation-induced complex DNA double-strand breaks
por: Yi, Geunil, et al.
Publicado: (2023)

Single-strand nicks induce homologous recombination with less toxicity than double-strand breaks using an AAV vector template
por: Metzger, Michael J., et al.
Publicado: (2011)

Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks
por: Dibitetto, Diego, et al.
Publicado: (2016)

Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair
por: Shahi, Ankita, et al.
Publicado: (2011)

Intra- and inter-molecular recombination of mitochondrial DNA after in vivo induction of multiple double-strand breaks
por: Bacman, Sandra R., et al.
Publicado: (2009)

SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination
por: Guan, Yongjuan, et al.
Publicado: (2022)

p21 promotes error-free replication-coupled DNA double-strand break repair
por: Mauro, Maurizio, et al.
Publicado: (2012)

The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair
por: Fenton, Amanda L., et al.
Publicado: (2013)

Phosphorylation of Ku dictates DNA double-strand break (DSB) repair pathway choice in S phase
por: Lee, Kyung-Jong, et al.
Publicado: (2016)

Secondary structure forming sequences drive SD-MMEJ repair of DNA double-strand breaks
por: Khodaverdian, Varandt Y., et al.
Publicado: (2017)

Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks
por: Feng, Wanjuan, et al.
Publicado: (2021)

HDGFRP3 interaction with 53BP1 promotes DNA double-strand break repair
por: Zhang, Zhen, et al.
Publicado: (2023)

DNA double-strand breaks with 5′ adducts are efficiently channeled to the DNA2-mediated resection pathway
por: Tammaro, Margaret, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_hpli1hsa306rkpl1gkm4vl2sqk