Cargando…

Nucleolar responses to DNA double-strand breaks

Maintenance of cellular homeostasis is key to prevent transformation and disease. The cellular response to DNA double-strand breaks, primarily orchestrated by the ATM/ATR kinases is one of many mechanisms that serve to uphold genome stability and homeostasis. Upon detection of double-strand breaks (...

Descripción completa

Detalles Bibliográficos
Autores principales: Larsen, Dorthe Helena, Stucki, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737151/
https://www.ncbi.nlm.nih.gov/pubmed/26615196
http://dx.doi.org/10.1093/nar/gkv1312