Cold-inducible RNA-binding protein CIRP/hnRNP A18 regulates telomerase activity in a temperature-dependent manner

The telomerase is responsible for adding telomeric repeats to chromosomal ends and consists of the reverse transcriptase TERT and the RNA subunit TERC. The expression and activity of the telomerase are tightly regulated, and aberrant activation of the telomerase has been observed in >85% of human...

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Detalles Bibliográficos
Autores principales: Zhang, Youwei, Wu, Yangxiu, Mao, Pingsu, Li, Feng, Han, Xin, Zhang, Yi, Jiang, Shuai, Chen, Yuxi, Huang, Junjiu, Liu, Dan, Zhao, Yong, Ma, Wenbin, Songyang, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737163/
https://www.ncbi.nlm.nih.gov/pubmed/26673712
http://dx.doi.org/10.1093/nar/gkv1465

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