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Simultaneous characterization of cellular RNA structure and function with in-cell SHAPE-Seq
Many non-coding RNAs form structures that interact with cellular machinery to control gene expression. A central goal of molecular and synthetic biology is to uncover design principles linking RNA structure to function to understand and engineer this relationship. Here we report a simple, high-throu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737173/ https://www.ncbi.nlm.nih.gov/pubmed/26350218 http://dx.doi.org/10.1093/nar/gkv879 |