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Adapting capillary gel electrophoresis as a sensitive, high-throughput method to accelerate characterization of nucleic acid metabolic enzymes

Detailed biochemical characterization of nucleic acid enzymes is fundamental to understanding nucleic acid metabolism, genome replication and repair. We report the development of a rapid, high-throughput fluorescence capillary gel electrophoresis method as an alternative to traditional polyacrylamid...

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Detalles Bibliográficos
Autores principales: Greenough, Lucia, Schermerhorn, Kelly M., Mazzola, Laurie, Bybee, Joanna, Rivizzigno, Danielle, Cantin, Elizabeth, Slatko, Barton E., Gardner, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737176/
https://www.ncbi.nlm.nih.gov/pubmed/26365239
http://dx.doi.org/10.1093/nar/gkv899