The activity of CouR, a MarR family transcriptional regulator, is modulated through a novel molecular mechanism

CouR, a MarR-type transcriptional repressor, regulates the cou genes, encoding p-hydroxycinnamate catabolism in the soil bacterium Rhodococcus jostii RHA1. The CouR dimer bound two molecules of the catabolite p-coumaroyl–CoA (K(d) = 11 ± 1 μM). The presence of p-coumaroyl–CoA, but neither p-coumarat...

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Detalles Bibliográficos
Autores principales: Otani, Hiroshi, Stogios, Peter J., Xu, Xiaohui, Nocek, Boguslaw, Li, Shu-Nan, Savchenko, Alexei, Eltis, Lindsay D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737184/
https://www.ncbi.nlm.nih.gov/pubmed/26400178
http://dx.doi.org/10.1093/nar/gkv955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737184/
https://www.ncbi.nlm.nih.gov/pubmed/26400178
http://dx.doi.org/10.1093/nar/gkv955

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