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The activity of CouR, a MarR family transcriptional regulator, is modulated through a novel molecular mechanism
CouR, a MarR-type transcriptional repressor, regulates the cou genes, encoding p-hydroxycinnamate catabolism in the soil bacterium Rhodococcus jostii RHA1. The CouR dimer bound two molecules of the catabolite p-coumaroyl–CoA (K(d) = 11 ± 1 μM). The presence of p-coumaroyl–CoA, but neither p-coumarat...
Autores principales: | Otani, Hiroshi, Stogios, Peter J., Xu, Xiaohui, Nocek, Boguslaw, Li, Shu-Nan, Savchenko, Alexei, Eltis, Lindsay D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737184/ https://www.ncbi.nlm.nih.gov/pubmed/26400178 http://dx.doi.org/10.1093/nar/gkv955 |
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