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Prediction of stability changes upon mutation in an icosahedral capsid
Identifying the contributions to thermodynamic stability of capsids is of fundamental and practical importance. Here we use simulation to assess how mutations affect the stability of lumazine synthase from the hyperthermophile Aquifex aeolicus, a T = 1 icosahedral capsid; in the simulations the icos...
Autores principales: | Hickman, Samuel J., Ross, James F., Paci, Emanuele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737204/ https://www.ncbi.nlm.nih.gov/pubmed/26178267 http://dx.doi.org/10.1002/prot.24859 |
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