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Prediction of stability changes upon mutation in an icosahedral capsid

Identifying the contributions to thermodynamic stability of capsids is of fundamental and practical importance. Here we use simulation to assess how mutations affect the stability of lumazine synthase from the hyperthermophile Aquifex aeolicus, a T = 1 icosahedral capsid; in the simulations the icos...

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Detalles Bibliográficos
Autores principales: Hickman, Samuel J., Ross, James F., Paci, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737204/
https://www.ncbi.nlm.nih.gov/pubmed/26178267
http://dx.doi.org/10.1002/prot.24859

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