Decreased Npas4 and Arc mRNA Levels in the Hippocampus of Aged Memory‐Impaired Wild‐Type But Not Memory Preserved 11β‐HSD1 Deficient Mice

Mice deficient in the glucocorticoid‐regenerating enzyme 11β‐HSD1 resist age‐related spatial memory impairment. To investigate the mechanisms and pathways involved, we used microarrays to identify differentially expressed hippocampal genes that associate with cognitive ageing and 11β‐HSD1. Aged wild...

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Detalles Bibliográficos
Autores principales: Qiu, J., Dunbar, D. R., Noble, J., Cairns, C., Carter, R., Kelly, V., Chapman, K. E., Seckl, J. R., Yau, J. L. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737280/
https://www.ncbi.nlm.nih.gov/pubmed/26563879
http://dx.doi.org/10.1111/jne.12339

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