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Engineering large animal models of human disease

The recent development of gene editing tools and methodology for use in livestock enables the production of new animal disease models. These tools facilitate site‐specific mutation of the genome, allowing animals carrying known human disease mutations to be produced. In this review, we describe the...

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Detalles Bibliográficos
Autores principales:	Whitelaw, C Bruce A, Sheets, Timothy P, Lillico, Simon G, Telugu, Bhanu P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Invited Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737318/ https://www.ncbi.nlm.nih.gov/pubmed/26414877 http://dx.doi.org/10.1002/path.4648

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