Cargando…
Metastatic lymph node ratio, 6th or 7th AJCC edition: witch is the best lymph node classification for esophageal cancer? Prognosis factor analysis in 487 patients
BACKGROUND: The esophageal cancer is one of the most common and aggressive worldwide. Recently, the AJCC changed the staging system, considering, among others, the important role of the lymph node metastasis on the prognosis. AIM: To discuss the applicability of different forms of lymph node staging...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Colégio Brasileiro de Cirurgia Digestiva
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737327/ https://www.ncbi.nlm.nih.gov/pubmed/26176242 http://dx.doi.org/10.1590/S0102-67202015000200002 |
_version_ | 1782413464536350720 |
---|---|
author | CORAL, Roberto V. BIGOLIN, André V. CORAL, Roberto P. HARTMANN, Antonio DRANKA, Carolina ROEHE, Adriana V. |
author_facet | CORAL, Roberto V. BIGOLIN, André V. CORAL, Roberto P. HARTMANN, Antonio DRANKA, Carolina ROEHE, Adriana V. |
author_sort | CORAL, Roberto V. |
collection | PubMed |
description | BACKGROUND: The esophageal cancer is one of the most common and aggressive worldwide. Recently, the AJCC changed the staging system, considering, among others, the important role of the lymph node metastasis on the prognosis. AIM: To discuss the applicability of different forms of lymph node staging in a western surgical center. METHODS: Four hundred eighty seven patients with esophageal cancer were enrolled. Three staging systems were evaluated, the 6(th) and the 7(th) AJCC editions and the Lymph Node Metastatic Ratio. RESULTS: The majority of the cases were squamous cell carcinoma. The mean lymph node sample was eight. Considering the survival, there was no significant difference between the patients when they were classified by the 7(th) AJCC edition. Analysis of the Lymph Node Metastatic Ratio, just on the group of patients with 0 to 25%, has shown significant difference (p=0,01). The 6(th) AJCC edition shows the major significant difference between among the classifications evaluated. CONCLUSION: In this specific population, the 7(th) AJCC edition for esophageal cancer was not able to find differences in survival when just the lymph node analysis was considered. |
format | Online Article Text |
id | pubmed-4737327 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Colégio Brasileiro de Cirurgia Digestiva |
record_format | MEDLINE/PubMed |
spelling | pubmed-47373272016-02-24 Metastatic lymph node ratio, 6th or 7th AJCC edition: witch is the best lymph node classification for esophageal cancer? Prognosis factor analysis in 487 patients CORAL, Roberto V. BIGOLIN, André V. CORAL, Roberto P. HARTMANN, Antonio DRANKA, Carolina ROEHE, Adriana V. Arq Bras Cir Dig Original Article BACKGROUND: The esophageal cancer is one of the most common and aggressive worldwide. Recently, the AJCC changed the staging system, considering, among others, the important role of the lymph node metastasis on the prognosis. AIM: To discuss the applicability of different forms of lymph node staging in a western surgical center. METHODS: Four hundred eighty seven patients with esophageal cancer were enrolled. Three staging systems were evaluated, the 6(th) and the 7(th) AJCC editions and the Lymph Node Metastatic Ratio. RESULTS: The majority of the cases were squamous cell carcinoma. The mean lymph node sample was eight. Considering the survival, there was no significant difference between the patients when they were classified by the 7(th) AJCC edition. Analysis of the Lymph Node Metastatic Ratio, just on the group of patients with 0 to 25%, has shown significant difference (p=0,01). The 6(th) AJCC edition shows the major significant difference between among the classifications evaluated. CONCLUSION: In this specific population, the 7(th) AJCC edition for esophageal cancer was not able to find differences in survival when just the lymph node analysis was considered. Colégio Brasileiro de Cirurgia Digestiva 2015 /pmc/articles/PMC4737327/ /pubmed/26176242 http://dx.doi.org/10.1590/S0102-67202015000200002 Text en http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article CORAL, Roberto V. BIGOLIN, André V. CORAL, Roberto P. HARTMANN, Antonio DRANKA, Carolina ROEHE, Adriana V. Metastatic lymph node ratio, 6th or 7th AJCC edition: witch is the best lymph node classification for esophageal cancer? Prognosis factor analysis in 487 patients |
title | Metastatic lymph node ratio, 6th or 7th AJCC edition: witch is the best
lymph node classification for esophageal cancer? Prognosis factor analysis in 487
patients |
title_full | Metastatic lymph node ratio, 6th or 7th AJCC edition: witch is the best
lymph node classification for esophageal cancer? Prognosis factor analysis in 487
patients |
title_fullStr | Metastatic lymph node ratio, 6th or 7th AJCC edition: witch is the best
lymph node classification for esophageal cancer? Prognosis factor analysis in 487
patients |
title_full_unstemmed | Metastatic lymph node ratio, 6th or 7th AJCC edition: witch is the best
lymph node classification for esophageal cancer? Prognosis factor analysis in 487
patients |
title_short | Metastatic lymph node ratio, 6th or 7th AJCC edition: witch is the best
lymph node classification for esophageal cancer? Prognosis factor analysis in 487
patients |
title_sort | metastatic lymph node ratio, 6th or 7th ajcc edition: witch is the best
lymph node classification for esophageal cancer? prognosis factor analysis in 487
patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737327/ https://www.ncbi.nlm.nih.gov/pubmed/26176242 http://dx.doi.org/10.1590/S0102-67202015000200002 |
work_keys_str_mv | AT coralrobertov metastaticlymphnoderatio6thor7thajcceditionwitchisthebestlymphnodeclassificationforesophagealcancerprognosisfactoranalysisin487patients AT bigolinandrev metastaticlymphnoderatio6thor7thajcceditionwitchisthebestlymphnodeclassificationforesophagealcancerprognosisfactoranalysisin487patients AT coralrobertop metastaticlymphnoderatio6thor7thajcceditionwitchisthebestlymphnodeclassificationforesophagealcancerprognosisfactoranalysisin487patients AT hartmannantonio metastaticlymphnoderatio6thor7thajcceditionwitchisthebestlymphnodeclassificationforesophagealcancerprognosisfactoranalysisin487patients AT drankacarolina metastaticlymphnoderatio6thor7thajcceditionwitchisthebestlymphnodeclassificationforesophagealcancerprognosisfactoranalysisin487patients AT roeheadrianav metastaticlymphnoderatio6thor7thajcceditionwitchisthebestlymphnodeclassificationforesophagealcancerprognosisfactoranalysisin487patients |