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Surgical treatment analysis of idiopathic esophageal achalasia

BACKGROUND: Idiopathic esophageal achalasia is an inflammatory disease of unknown origin, characterized by aperistalsis of the esophageal body and failure of the lower esophageal sphincter in response to swallowing, with consequent dysphagia. AIM: To demonstrate the results of surgical therapy in th...

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Autores principales: de AQUINO, José Luis Braga, SAID, Marcelo Manzano, PEREIRA, Douglas Rizzanti, do AMARAL, Paula Casals, LIMA, Juliana Carolina Alves, LEANDRO-MERHI, Vânia Aparecida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737328/
https://www.ncbi.nlm.nih.gov/pubmed/26176243
http://dx.doi.org/10.1590/S0102-67202015000200003
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author de AQUINO, José Luis Braga
SAID, Marcelo Manzano
PEREIRA, Douglas Rizzanti
do AMARAL, Paula Casals
LIMA, Juliana Carolina Alves
LEANDRO-MERHI, Vânia Aparecida
author_facet de AQUINO, José Luis Braga
SAID, Marcelo Manzano
PEREIRA, Douglas Rizzanti
do AMARAL, Paula Casals
LIMA, Juliana Carolina Alves
LEANDRO-MERHI, Vânia Aparecida
author_sort de AQUINO, José Luis Braga
collection PubMed
description BACKGROUND: Idiopathic esophageal achalasia is an inflammatory disease of unknown origin, characterized by aperistalsis of the esophageal body and failure of the lower esophageal sphincter in response to swallowing, with consequent dysphagia. AIM: To demonstrate the results of surgical therapy in these patients, evaluating the occurred local and systemic complications. METHODS: Were studied retrospectively 32 patients, 22 of whom presented non-advanced stage of the disease (Stage I/II) and 10 with advanced disease (Stage III/IV). All of them had the clinical conditions to be submitted to surgery. The diagnoses were done by clinical, endoscopic, cardiological, radiological and esophageal manometry analysis. Pre-surgical evaluation was done with a questionnaire based on the most predisposing factors in the development of the disease and the surgical indication was based on the stage of the disease. RESULTS: The patients with non-advanced stages were submitted to cardiomyotomy with fundoplication, wherein in the post-surgical early assessment, only one (4,4%) presented pulmonary infection, but had a good outcome. In patients with advanced disease, seven were submitted to esophageal mucosectomy preserving the muscular layer, wherein one patient (14,2%) presented dehiscence of gastric cervical esophagus anastomosis as well as pulmonary infection; all of these complications were resolved with proper specific treatment; the other three patients with advanced stage were submitted to transmediastinal esophagectomy; two of them presented hydropneumothorax with good evolution, and one of them also presented fistula of the cervical esophagogastric anastomosis, but with spontaneous healing after conservative treatment and nutritional support. The two patients with fistula of the cervical anastomosis progressed to stenosis, with good results after endoscopic dilations. In the medium and long term assessment done in 23 patients, all of them reported improvement in life quality, with return to swallowing. CONCLUSION: The strategy proposed for the surgical treatment of idiopathic esophageal achalasia according to the stages of the disease was of great value, due to post-surgical low morbidity complications and proper recovery of swallowing.
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spelling pubmed-47373282016-02-24 Surgical treatment analysis of idiopathic esophageal achalasia de AQUINO, José Luis Braga SAID, Marcelo Manzano PEREIRA, Douglas Rizzanti do AMARAL, Paula Casals LIMA, Juliana Carolina Alves LEANDRO-MERHI, Vânia Aparecida Arq Bras Cir Dig Original Article BACKGROUND: Idiopathic esophageal achalasia is an inflammatory disease of unknown origin, characterized by aperistalsis of the esophageal body and failure of the lower esophageal sphincter in response to swallowing, with consequent dysphagia. AIM: To demonstrate the results of surgical therapy in these patients, evaluating the occurred local and systemic complications. METHODS: Were studied retrospectively 32 patients, 22 of whom presented non-advanced stage of the disease (Stage I/II) and 10 with advanced disease (Stage III/IV). All of them had the clinical conditions to be submitted to surgery. The diagnoses were done by clinical, endoscopic, cardiological, radiological and esophageal manometry analysis. Pre-surgical evaluation was done with a questionnaire based on the most predisposing factors in the development of the disease and the surgical indication was based on the stage of the disease. RESULTS: The patients with non-advanced stages were submitted to cardiomyotomy with fundoplication, wherein in the post-surgical early assessment, only one (4,4%) presented pulmonary infection, but had a good outcome. In patients with advanced disease, seven were submitted to esophageal mucosectomy preserving the muscular layer, wherein one patient (14,2%) presented dehiscence of gastric cervical esophagus anastomosis as well as pulmonary infection; all of these complications were resolved with proper specific treatment; the other three patients with advanced stage were submitted to transmediastinal esophagectomy; two of them presented hydropneumothorax with good evolution, and one of them also presented fistula of the cervical esophagogastric anastomosis, but with spontaneous healing after conservative treatment and nutritional support. The two patients with fistula of the cervical anastomosis progressed to stenosis, with good results after endoscopic dilations. In the medium and long term assessment done in 23 patients, all of them reported improvement in life quality, with return to swallowing. CONCLUSION: The strategy proposed for the surgical treatment of idiopathic esophageal achalasia according to the stages of the disease was of great value, due to post-surgical low morbidity complications and proper recovery of swallowing. Colégio Brasileiro de Cirurgia Digestiva 2015 /pmc/articles/PMC4737328/ /pubmed/26176243 http://dx.doi.org/10.1590/S0102-67202015000200003 Text en http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
de AQUINO, José Luis Braga
SAID, Marcelo Manzano
PEREIRA, Douglas Rizzanti
do AMARAL, Paula Casals
LIMA, Juliana Carolina Alves
LEANDRO-MERHI, Vânia Aparecida
Surgical treatment analysis of idiopathic esophageal achalasia
title Surgical treatment analysis of idiopathic esophageal achalasia
title_full Surgical treatment analysis of idiopathic esophageal achalasia
title_fullStr Surgical treatment analysis of idiopathic esophageal achalasia
title_full_unstemmed Surgical treatment analysis of idiopathic esophageal achalasia
title_short Surgical treatment analysis of idiopathic esophageal achalasia
title_sort surgical treatment analysis of idiopathic esophageal achalasia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737328/
https://www.ncbi.nlm.nih.gov/pubmed/26176243
http://dx.doi.org/10.1590/S0102-67202015000200003
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