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LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA

BACKGROUND: The lactate is a product of anaerobic metabolism; it can be used as a marker on demand and availability of oxygen. Changes in lactate levels can be effectively used as a marker in resuscitation maneuvers, even in patients with stable vital signs. AIM: To verify the lactate clearance as a...

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Detalles Bibliográficos
Autores principales: FREITAS, Andréia Diane, FRANZON, Orli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737353/
https://www.ncbi.nlm.nih.gov/pubmed/26537138
http://dx.doi.org/10.1590/S0102-67202015000300004
Descripción
Sumario:BACKGROUND: The lactate is a product of anaerobic metabolism; it can be used as a marker on demand and availability of oxygen. Changes in lactate levels can be effectively used as a marker in resuscitation maneuvers, even in patients with stable vital signs. AIM: To verify the lactate clearance as a predictor of mortality in trauma patients, in need of intensive care. METHOD: A total of 851 patients were admitted in ICU, in which 146 were victims of multiple trauma; due to the exclusion criteria, were included 117. RESULTS: Patients were 87% male, mean age 32.4 years, motorcycle drivers, Glasgow coma scale between 3-8, affected by cranial trauma, followed by abdominal trauma. Was verified mortality up to 48 h and global mortality, that did not show statistical relationship between lactate clearance and mortality (p=0.928). CONCLUSION: There is no correlation between admission lactate or lactate clearance and mortality in patients treated with multiple trauma.