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LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA

BACKGROUND: The lactate is a product of anaerobic metabolism; it can be used as a marker on demand and availability of oxygen. Changes in lactate levels can be effectively used as a marker in resuscitation maneuvers, even in patients with stable vital signs. AIM: To verify the lactate clearance as a...

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Detalles Bibliográficos
Autores principales: FREITAS, Andréia Diane, FRANZON, Orli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737353/
https://www.ncbi.nlm.nih.gov/pubmed/26537138
http://dx.doi.org/10.1590/S0102-67202015000300004
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author FREITAS, Andréia Diane
FRANZON, Orli
author_facet FREITAS, Andréia Diane
FRANZON, Orli
author_sort FREITAS, Andréia Diane
collection PubMed
description BACKGROUND: The lactate is a product of anaerobic metabolism; it can be used as a marker on demand and availability of oxygen. Changes in lactate levels can be effectively used as a marker in resuscitation maneuvers, even in patients with stable vital signs. AIM: To verify the lactate clearance as a predictor of mortality in trauma patients, in need of intensive care. METHOD: A total of 851 patients were admitted in ICU, in which 146 were victims of multiple trauma; due to the exclusion criteria, were included 117. RESULTS: Patients were 87% male, mean age 32.4 years, motorcycle drivers, Glasgow coma scale between 3-8, affected by cranial trauma, followed by abdominal trauma. Was verified mortality up to 48 h and global mortality, that did not show statistical relationship between lactate clearance and mortality (p=0.928). CONCLUSION: There is no correlation between admission lactate or lactate clearance and mortality in patients treated with multiple trauma.
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spelling pubmed-47373532016-02-24 LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA FREITAS, Andréia Diane FRANZON, Orli Arq Bras Cir Dig Original Article BACKGROUND: The lactate is a product of anaerobic metabolism; it can be used as a marker on demand and availability of oxygen. Changes in lactate levels can be effectively used as a marker in resuscitation maneuvers, even in patients with stable vital signs. AIM: To verify the lactate clearance as a predictor of mortality in trauma patients, in need of intensive care. METHOD: A total of 851 patients were admitted in ICU, in which 146 were victims of multiple trauma; due to the exclusion criteria, were included 117. RESULTS: Patients were 87% male, mean age 32.4 years, motorcycle drivers, Glasgow coma scale between 3-8, affected by cranial trauma, followed by abdominal trauma. Was verified mortality up to 48 h and global mortality, that did not show statistical relationship between lactate clearance and mortality (p=0.928). CONCLUSION: There is no correlation between admission lactate or lactate clearance and mortality in patients treated with multiple trauma. Colégio Brasileiro de Cirurgia Digestiva 2015 /pmc/articles/PMC4737353/ /pubmed/26537138 http://dx.doi.org/10.1590/S0102-67202015000300004 Text en http://creativecommons.org/licenses/by/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
FREITAS, Andréia Diane
FRANZON, Orli
LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA
title LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA
title_full LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA
title_fullStr LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA
title_full_unstemmed LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA
title_short LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA
title_sort lactate as predictor of mortality in polytrauma
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737353/
https://www.ncbi.nlm.nih.gov/pubmed/26537138
http://dx.doi.org/10.1590/S0102-67202015000300004
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