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LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA
BACKGROUND: The lactate is a product of anaerobic metabolism; it can be used as a marker on demand and availability of oxygen. Changes in lactate levels can be effectively used as a marker in resuscitation maneuvers, even in patients with stable vital signs. AIM: To verify the lactate clearance as a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Colégio Brasileiro de Cirurgia Digestiva
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737353/ https://www.ncbi.nlm.nih.gov/pubmed/26537138 http://dx.doi.org/10.1590/S0102-67202015000300004 |
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author | FREITAS, Andréia Diane FRANZON, Orli |
author_facet | FREITAS, Andréia Diane FRANZON, Orli |
author_sort | FREITAS, Andréia Diane |
collection | PubMed |
description | BACKGROUND: The lactate is a product of anaerobic metabolism; it can be used as a marker on demand and availability of oxygen. Changes in lactate levels can be effectively used as a marker in resuscitation maneuvers, even in patients with stable vital signs. AIM: To verify the lactate clearance as a predictor of mortality in trauma patients, in need of intensive care. METHOD: A total of 851 patients were admitted in ICU, in which 146 were victims of multiple trauma; due to the exclusion criteria, were included 117. RESULTS: Patients were 87% male, mean age 32.4 years, motorcycle drivers, Glasgow coma scale between 3-8, affected by cranial trauma, followed by abdominal trauma. Was verified mortality up to 48 h and global mortality, that did not show statistical relationship between lactate clearance and mortality (p=0.928). CONCLUSION: There is no correlation between admission lactate or lactate clearance and mortality in patients treated with multiple trauma. |
format | Online Article Text |
id | pubmed-4737353 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Colégio Brasileiro de Cirurgia Digestiva |
record_format | MEDLINE/PubMed |
spelling | pubmed-47373532016-02-24 LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA FREITAS, Andréia Diane FRANZON, Orli Arq Bras Cir Dig Original Article BACKGROUND: The lactate is a product of anaerobic metabolism; it can be used as a marker on demand and availability of oxygen. Changes in lactate levels can be effectively used as a marker in resuscitation maneuvers, even in patients with stable vital signs. AIM: To verify the lactate clearance as a predictor of mortality in trauma patients, in need of intensive care. METHOD: A total of 851 patients were admitted in ICU, in which 146 were victims of multiple trauma; due to the exclusion criteria, were included 117. RESULTS: Patients were 87% male, mean age 32.4 years, motorcycle drivers, Glasgow coma scale between 3-8, affected by cranial trauma, followed by abdominal trauma. Was verified mortality up to 48 h and global mortality, that did not show statistical relationship between lactate clearance and mortality (p=0.928). CONCLUSION: There is no correlation between admission lactate or lactate clearance and mortality in patients treated with multiple trauma. Colégio Brasileiro de Cirurgia Digestiva 2015 /pmc/articles/PMC4737353/ /pubmed/26537138 http://dx.doi.org/10.1590/S0102-67202015000300004 Text en http://creativecommons.org/licenses/by/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License |
spellingShingle | Original Article FREITAS, Andréia Diane FRANZON, Orli LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA |
title | LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA |
title_full | LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA |
title_fullStr | LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA |
title_full_unstemmed | LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA |
title_short | LACTATE AS PREDICTOR OF MORTALITY IN POLYTRAUMA |
title_sort | lactate as predictor of mortality in polytrauma |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737353/ https://www.ncbi.nlm.nih.gov/pubmed/26537138 http://dx.doi.org/10.1590/S0102-67202015000300004 |
work_keys_str_mv | AT freitasandreiadiane lactateaspredictorofmortalityinpolytrauma AT franzonorli lactateaspredictorofmortalityinpolytrauma |