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Caspase-3/7-mediated Cleavage of β2-spectrin is Required for Acetaminophen-induced Liver Damage

The ubiquitously expressed β2-spectrin (β2SP, SPTBN1) is the most common non-erythrocytic member of the β-spectrin gene family. Loss of β2-spectrin leads to defects in liver development, and its haploinsufficiency spontaneously leads to chronic liver disease and the eventual development of hepatocel...

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Detalles Bibliográficos
Autores principales:	Baek, Hye Jung, Lee, Yong Min, Kim, Tae Hyun, Kim, Joo-Young, Park, Eun Jung, Iwabuchi, Kuniyoshi, Mishra, Lopa, Kim, Sang Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737674/ https://www.ncbi.nlm.nih.gov/pubmed/26884715 http://dx.doi.org/10.7150/ijbs.13420

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