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Diabetes Induced Changes in Podocyte Morphology and Gene Expression Evaluated Using GFP Transgenic Podocytes
The effect of diabetes in vivo has not been examined on isolated podocytes. To achieve this, GFP was expressed constitutively in podocytes of PGFP transgenic mice which were bred to OVE mice to produce diabetic OVE-GFP mice. Viewing GFP fluorescence, foot processes of OVE-GFP podocytes were visually...
Autores principales: | Xu, Jianxiang, Zheng, Shirong, Kralik, Patricia M., Krishnan, Laxminarayanan, Huang, Hui, Hoying, James B., Cai, Lu, Carlson, Edward C., Tan, Yi, Epstein, Paul N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737677/ https://www.ncbi.nlm.nih.gov/pubmed/26884718 http://dx.doi.org/10.7150/ijbs.13057 |
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