BMPR2 mutations and survival in pulmonary arterial hypertension: an individual participant data meta-analysis

BACKGROUND: Mutations in the gene encoding the bone morphogenetic protein receptor type II (BMPR2) are the commonest genetic cause of pulmonary arterial hypertension (PAH). However, the effect of BMPR2 mutations on clinical phenotype and outcomes remains uncertain. METHODS: We analysed individual pa...

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Detalles Bibliográficos
Autores principales: Evans, Jonathan D W, Girerd, Barbara, Montani, David, Wang, Xiao-Jian, Galiè, Nazzareno, Austin, Eric D, Elliott, Greg, Asano, Koichiro, Grünig, Ekkehard, Yan, Yi, Jing, Zhi-Cheng, Manes, Alessandra, Palazzini, Massimiliano, Wheeler, Lisa A, Nakayama, Ikue, Satoh, Toru, Eichstaedt, Christina, Hinderhofer, Katrin, Wolf, Matthias, Rosenzweig, Erika B, Chung, Wendy K, Soubrier, Florent, Simonneau, Gérald, Sitbon, Olivier, Gräf, Stefan, Kaptoge, Stephen, Di Angelantonio, Emanuele, Humbert, Marc, Morrell, Nicholas W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737700/
https://www.ncbi.nlm.nih.gov/pubmed/26795434
http://dx.doi.org/10.1016/S2213-2600(15)00544-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737700/
https://www.ncbi.nlm.nih.gov/pubmed/26795434
http://dx.doi.org/10.1016/S2213-2600(15)00544-5

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