Image-aided Suicide Gene Therapy Utilizing Multifunctional hTERT-targeting Adenovirus for Clinical Translation in Hepatocellular Carcinoma

Trans-splicing ribozyme enables to sense and reprogram target RNA into therapeutic transgene and thereby becomes a good sensing device for detection of cancer cells, judging from transgene expression. Previously we proposed PEPCK-Rz-HSVtk (PRT), hTERT targeting trans-splicing ribozyme (Rz) driven by...

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Detalles Bibliográficos
Autores principales: Kim, Yun-Hee, Kim, Kyung Tae, Lee, Sang-Jin, Hong, Seung-Hee, Moon, Ju Young, Yoon, Eun Kyung, Kim, Sukyoung, Kim, Eun Ok, Kang, Se Hun, Kim, Seok Ki, Choi, Sun Il, Goh, Sung Ho, Kim, Daehong, Lee, Seong-Wook, Ju, Mi Ha, Jeong, Jin Sook, Kim, In-Hoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737723/
https://www.ncbi.nlm.nih.gov/pubmed/26909111
http://dx.doi.org/10.7150/thno.13621

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