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Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells
Self-renewing tissue-resident macrophages are thought to be exclusively derived from embryonic progenitors. However, whether circulating monocytes can also give rise to such macrophages has not been formally investigated. Here we use a new model of diphtheria toxin-mediated depletion of liver-reside...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737801/ https://www.ncbi.nlm.nih.gov/pubmed/26813785 http://dx.doi.org/10.1038/ncomms10321 |