Hemorrhagic Fever with Renal Syndrome: Pathogenesis and Clinical Picture

Hantaan virus (HTNV) causes hemorrhagic fever with renal syndrome (HFRS), which is a zoonosis endemic in eastern Asia, especially in China. The reservoir host of HTNV is field mouse (Apodemus agraricus). The main manifestation of HFRS, including acute kidney injury, increases vascular permeability,...

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Detalles Bibliográficos
Autores principales: Jiang, Hong, Du, Hong, Wang, Li M., Wang, Ping Z., Bai, Xue F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737898/
https://www.ncbi.nlm.nih.gov/pubmed/26870699
http://dx.doi.org/10.3389/fcimb.2016.00001
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author Jiang, Hong
Du, Hong
Wang, Li M.
Wang, Ping Z.
Bai, Xue F.
author_facet Jiang, Hong
Du, Hong
Wang, Li M.
Wang, Ping Z.
Bai, Xue F.
author_sort Jiang, Hong
collection PubMed
description Hantaan virus (HTNV) causes hemorrhagic fever with renal syndrome (HFRS), which is a zoonosis endemic in eastern Asia, especially in China. The reservoir host of HTNV is field mouse (Apodemus agraricus). The main manifestation of HFRS, including acute kidney injury, increases vascular permeability, and coagulation abnormalities. In this paper, we review the current knowledge of the pathogenesis of HFRS including virus factor, immunity factor and host genetic factors. Furthermore, the treatment and prevention will be discussed.
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spelling pubmed-47378982016-02-11 Hemorrhagic Fever with Renal Syndrome: Pathogenesis and Clinical Picture Jiang, Hong Du, Hong Wang, Li M. Wang, Ping Z. Bai, Xue F. Front Cell Infect Microbiol Microbiology Hantaan virus (HTNV) causes hemorrhagic fever with renal syndrome (HFRS), which is a zoonosis endemic in eastern Asia, especially in China. The reservoir host of HTNV is field mouse (Apodemus agraricus). The main manifestation of HFRS, including acute kidney injury, increases vascular permeability, and coagulation abnormalities. In this paper, we review the current knowledge of the pathogenesis of HFRS including virus factor, immunity factor and host genetic factors. Furthermore, the treatment and prevention will be discussed. Frontiers Media S.A. 2016-02-03 /pmc/articles/PMC4737898/ /pubmed/26870699 http://dx.doi.org/10.3389/fcimb.2016.00001 Text en Copyright © 2016 Jiang, Du, Wang, Wang and Bai. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Jiang, Hong
Du, Hong
Wang, Li M.
Wang, Ping Z.
Bai, Xue F.
Hemorrhagic Fever with Renal Syndrome: Pathogenesis and Clinical Picture
title Hemorrhagic Fever with Renal Syndrome: Pathogenesis and Clinical Picture
title_full Hemorrhagic Fever with Renal Syndrome: Pathogenesis and Clinical Picture
title_fullStr Hemorrhagic Fever with Renal Syndrome: Pathogenesis and Clinical Picture
title_full_unstemmed Hemorrhagic Fever with Renal Syndrome: Pathogenesis and Clinical Picture
title_short Hemorrhagic Fever with Renal Syndrome: Pathogenesis and Clinical Picture
title_sort hemorrhagic fever with renal syndrome: pathogenesis and clinical picture
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737898/
https://www.ncbi.nlm.nih.gov/pubmed/26870699
http://dx.doi.org/10.3389/fcimb.2016.00001
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AT wangpingz hemorrhagicfeverwithrenalsyndromepathogenesisandclinicalpicture
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