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Persistence Increases in the Absence of the Alarmone Guanosine Tetraphosphate by Reducing Cell Growth
Most bacterial cells are stressed, and as a result, some become tolerant to antibiotics by entering a dormant state known as persistence. The key intracellular metabolite that has been linked to this persister state is guanosine tetraphosphate (ppGpp), the alarmone that was first linked to nutrient...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738310/ https://www.ncbi.nlm.nih.gov/pubmed/26837570 http://dx.doi.org/10.1038/srep20519 |