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A Hypersweet Protein: Removal of The Specific Negative Charge at Asp21 Enhances Thaumatin Sweetness
Thaumatin is an intensely sweet-tasting protein that elicits sweet taste at a concentration of 50 nM, a value 100,000 times larger than that of sucrose on a molar basis. Here we attempted to produce a protein with enhanced sweetness by removing negative charges on the interacting side of thaumatin w...
Autores principales: | Masuda, Tetsuya, Ohta, Keisuke, Ojiro, Naoko, Murata, Kazuki, Mikami, Bunzo, Tani, Fumito, Temussi, Piero Andrea, Kitabatake, Naofumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738316/ https://www.ncbi.nlm.nih.gov/pubmed/26837600 http://dx.doi.org/10.1038/srep20255 |
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