Applying (89)Zr-Transferrin To Study the Pharmacology of Inhibitors to BET Bromodomain Containing Proteins

[Image: see text] Chromatin modifying proteins are attractive drug targets in oncology, given the fundamental reliance of cancer on altered transcriptional activity. Multiple transcription factors can be impacted downstream of primary target inhibition, thus making it challenging to understand the d...

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Detalles Bibliográficos
Autores principales: Doran, Michael G., Carnazza, Kathryn E., Steckler, Jeffrey M., Spratt, Daniel E., Truillet, Charles, Wongvipat, John, Sawyers, Charles L., Lewis, Jason S., Evans, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738321/
https://www.ncbi.nlm.nih.gov/pubmed/26725682
http://dx.doi.org/10.1021/acs.molpharmaceut.5b00882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738321/
https://www.ncbi.nlm.nih.gov/pubmed/26725682
http://dx.doi.org/10.1021/acs.molpharmaceut.5b00882

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