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Applying (89)Zr-Transferrin To Study the Pharmacology of Inhibitors to BET Bromodomain Containing Proteins
[Image: see text] Chromatin modifying proteins are attractive drug targets in oncology, given the fundamental reliance of cancer on altered transcriptional activity. Multiple transcription factors can be impacted downstream of primary target inhibition, thus making it challenging to understand the d...
Autores principales: | Doran, Michael G., Carnazza, Kathryn E., Steckler, Jeffrey M., Spratt, Daniel E., Truillet, Charles, Wongvipat, John, Sawyers, Charles L., Lewis, Jason S., Evans, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2016
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738321/ https://www.ncbi.nlm.nih.gov/pubmed/26725682 http://dx.doi.org/10.1021/acs.molpharmaceut.5b00882 |
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