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Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells

T follicular regulatory (Tfr) cells are a subset of Foxp3(+) regulatory T (Treg) cells that form in response to immunization or infection, which localize to the germinal centre where they control the magnitude of the response. Despite an increased interest in the role of Tfr cells in humoral immunit...

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Detalles Bibliográficos
Autores principales: Aloulou, Meryem, Carr, Edward J., Gador, Mylène, Bignon, Alexandre, Liblau, Roland S., Fazilleau, Nicolas, Linterman, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738360/
https://www.ncbi.nlm.nih.gov/pubmed/26818004
http://dx.doi.org/10.1038/ncomms10579

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