SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication

Maintenance of genome stability requires that DNA is replicated precisely once per cell cycle. This is believed to be achieved by limiting replication origin licensing and thereby restricting the firing of each replication origin to once per cell cycle. CDC6 is essential for eukaryotic replication o...

Descripción completa

Detalles Bibliográficos
Autores principales: Walter, David, Hoffmann, Saskia, Komseli, Eirini-Stavroula, Rappsilber, Juri, Gorgoulis, Vassilis, Sørensen, Claus Storgaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738361/
https://www.ncbi.nlm.nih.gov/pubmed/26818844
http://dx.doi.org/10.1038/ncomms10530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738361/
https://www.ncbi.nlm.nih.gov/pubmed/26818844
http://dx.doi.org/10.1038/ncomms10530

Ejemplares similares