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SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication
Maintenance of genome stability requires that DNA is replicated precisely once per cell cycle. This is believed to be achieved by limiting replication origin licensing and thereby restricting the firing of each replication origin to once per cell cycle. CDC6 is essential for eukaryotic replication o...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738361/ https://www.ncbi.nlm.nih.gov/pubmed/26818844 http://dx.doi.org/10.1038/ncomms10530 |