Cargando…
Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth
The precise architecture of hair bundles, the arrays of mechanosensitive microvilli-like stereocilia crowning the auditory hair cells, is essential to hearing. Myosin IIIa, defective in the late-onset deafness form DFNB30, has been proposed to transport espin-1 to the tips of stereocilia, thereby pr...
Autores principales: | Lelli, Andrea, Michel, Vincent, Boutet de Monvel, Jacques, Cortese, Matteo, Bosch-Grau, Montserrat, Aghaie, Asadollah, Perfettini, Isabelle, Dupont, Typhaine, Avan, Paul, El-Amraoui, Aziz, Petit, Christine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738386/ https://www.ncbi.nlm.nih.gov/pubmed/26754646 http://dx.doi.org/10.1083/jcb.201509017 |
Ejemplares similares
-
Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells
por: Michel, Vincent, et al.
Publicado: (2020) -
Control of stereocilia length during development of hair bundles
por: Krey, Jocelyn F., et al.
Publicado: (2023) -
CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival
por: Michel, Vincent, et al.
Publicado: (2017) -
Simulation of the Response of the Inner Hair Cell Stereocilia Bundle
to an Acoustical Stimulus
por: Smith, Sonya T., et al.
Publicado: (2011) -
MANF supports the inner hair cell synapse and the outer hair cell stereocilia bundle in the cochlea
por: Ikäheimo, Kuu, et al.
Publicado: (2021)