Independent Control of Topography for 3D Patterning of the ECM Microenvironment

Biomimetic extracellular matrix (ECM) topographies driven by the magnetic‐field‐directed self‐assembly of ECM protein‐coated magnetic beads are fabricated. This novel bottom‐up method allows us to program isotropic, anisotropic, and diverse hybrid ECM patterns without changing other physicochemical...

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Detalles Bibliográficos
Autores principales: Kim, Jiyun, Staunton, Jack Rory, Tanner, Kandice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738476/
https://www.ncbi.nlm.nih.gov/pubmed/26551393
http://dx.doi.org/10.1002/adma.201503950
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author Kim, Jiyun
Staunton, Jack Rory
Tanner, Kandice
author_facet Kim, Jiyun
Staunton, Jack Rory
Tanner, Kandice
author_sort Kim, Jiyun
collection PubMed
description Biomimetic extracellular matrix (ECM) topographies driven by the magnetic‐field‐directed self‐assembly of ECM protein‐coated magnetic beads are fabricated. This novel bottom‐up method allows us to program isotropic, anisotropic, and diverse hybrid ECM patterns without changing other physicochemical properties of the scaffold material. It is demonstrated that this 3D anisotropic matrix is able to guide the dendritic protrusion of cells. [Image: see text]
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spelling pubmed-47384762016-02-12 Independent Control of Topography for 3D Patterning of the ECM Microenvironment Kim, Jiyun Staunton, Jack Rory Tanner, Kandice Adv Mater Communications Biomimetic extracellular matrix (ECM) topographies driven by the magnetic‐field‐directed self‐assembly of ECM protein‐coated magnetic beads are fabricated. This novel bottom‐up method allows us to program isotropic, anisotropic, and diverse hybrid ECM patterns without changing other physicochemical properties of the scaffold material. It is demonstrated that this 3D anisotropic matrix is able to guide the dendritic protrusion of cells. [Image: see text] John Wiley and Sons Inc. 2015-11-09 2016-01 /pmc/articles/PMC4738476/ /pubmed/26551393 http://dx.doi.org/10.1002/adma.201503950 Text en © 2015 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Communications
Kim, Jiyun
Staunton, Jack Rory
Tanner, Kandice
Independent Control of Topography for 3D Patterning of the ECM Microenvironment
title Independent Control of Topography for 3D Patterning of the ECM Microenvironment
title_full Independent Control of Topography for 3D Patterning of the ECM Microenvironment
title_fullStr Independent Control of Topography for 3D Patterning of the ECM Microenvironment
title_full_unstemmed Independent Control of Topography for 3D Patterning of the ECM Microenvironment
title_short Independent Control of Topography for 3D Patterning of the ECM Microenvironment
title_sort independent control of topography for 3d patterning of the ecm microenvironment
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738476/
https://www.ncbi.nlm.nih.gov/pubmed/26551393
http://dx.doi.org/10.1002/adma.201503950
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