MiR-302a/b/c/d cooperatively sensitizes breast cancer cells to adriamycin via suppressing P-glycoprotein(P-gp) by targeting MAP/ERK kinase kinase 1 (MEKK1)

BACKGROUND: The importance of individual microRNAs (miRNAs) in tumor has been established in different cancers. However, their association with tumor chemoresistance has not been fully understood. Previously, we found two novel MDR-associated microRNAs (miRNAs). In this report, we investigated the c...

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Detalles Bibliográficos
Autores principales: Zhao, Lin, Wang, Yan, Jiang, Longyang, He, Miao, Bai, Xuefeng, Yu, Lifeng, Wei, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738800/
https://www.ncbi.nlm.nih.gov/pubmed/26842910
http://dx.doi.org/10.1186/s13046-016-0300-8

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