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Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis
Eosinophilic myocarditis (EM) represents a rare form of myocardial inflammation with very heterogeneous aetiology. In developed countries, the most prevalent causes of EM are hypersensitivity or allergic reactions, as well as hematological diseases leading to eosinophilia. The disease may have a var...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738989/ https://www.ncbi.nlm.nih.gov/pubmed/26885504 http://dx.doi.org/10.1155/2016/2829583 |
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author | Kuchynka, Petr Palecek, Tomas Masek, Martin Cerny, Vladimir Lambert, Lukas Vitkova, Ivana Linhart, Ales |
author_facet | Kuchynka, Petr Palecek, Tomas Masek, Martin Cerny, Vladimir Lambert, Lukas Vitkova, Ivana Linhart, Ales |
author_sort | Kuchynka, Petr |
collection | PubMed |
description | Eosinophilic myocarditis (EM) represents a rare form of myocardial inflammation with very heterogeneous aetiology. In developed countries, the most prevalent causes of EM are hypersensitivity or allergic reactions, as well as hematological diseases leading to eosinophilia. The disease may have a variable clinical presentation, ranging from asymptomatic forms to life-threatening conditions. Most patients with EM have marked eosinophilia in peripheral blood. Endomyocardial biopsy needs to be performed in most cases in order to establish a definitive diagnosis of EM. The therapy depends on the underlying aetiology. Immunosuppressive therapy represents the treatment mainstay in the majority of EM forms. |
format | Online Article Text |
id | pubmed-4738989 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-47389892016-02-16 Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis Kuchynka, Petr Palecek, Tomas Masek, Martin Cerny, Vladimir Lambert, Lukas Vitkova, Ivana Linhart, Ales Biomed Res Int Review Article Eosinophilic myocarditis (EM) represents a rare form of myocardial inflammation with very heterogeneous aetiology. In developed countries, the most prevalent causes of EM are hypersensitivity or allergic reactions, as well as hematological diseases leading to eosinophilia. The disease may have a variable clinical presentation, ranging from asymptomatic forms to life-threatening conditions. Most patients with EM have marked eosinophilia in peripheral blood. Endomyocardial biopsy needs to be performed in most cases in order to establish a definitive diagnosis of EM. The therapy depends on the underlying aetiology. Immunosuppressive therapy represents the treatment mainstay in the majority of EM forms. Hindawi Publishing Corporation 2016 2016-01-17 /pmc/articles/PMC4738989/ /pubmed/26885504 http://dx.doi.org/10.1155/2016/2829583 Text en Copyright © 2016 Petr Kuchynka et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Kuchynka, Petr Palecek, Tomas Masek, Martin Cerny, Vladimir Lambert, Lukas Vitkova, Ivana Linhart, Ales Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis |
title | Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis |
title_full | Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis |
title_fullStr | Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis |
title_full_unstemmed | Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis |
title_short | Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis |
title_sort | current diagnostic and therapeutic aspects of eosinophilic myocarditis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738989/ https://www.ncbi.nlm.nih.gov/pubmed/26885504 http://dx.doi.org/10.1155/2016/2829583 |
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