A review of the new HGNC gene family resource

The HUGO Gene Nomenclature Committee (HGNC) approves unique gene symbols and names for human loci. As well as naming genomic loci, we manually curate genes into family sets based on shared characteristics such as function, homology or phenotype. Each HGNC gene family has its own dedicated gene famil...

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Detalles Bibliográficos
Autores principales: Gray, Kristian A, Seal, Ruth L, Tweedie, Susan, Wright, Mathew W, Bruford, Elspeth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739092/
https://www.ncbi.nlm.nih.gov/pubmed/26842383
http://dx.doi.org/10.1186/s40246-016-0062-6
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author Gray, Kristian A
Seal, Ruth L
Tweedie, Susan
Wright, Mathew W
Bruford, Elspeth A
author_facet Gray, Kristian A
Seal, Ruth L
Tweedie, Susan
Wright, Mathew W
Bruford, Elspeth A
author_sort Gray, Kristian A
collection PubMed
description The HUGO Gene Nomenclature Committee (HGNC) approves unique gene symbols and names for human loci. As well as naming genomic loci, we manually curate genes into family sets based on shared characteristics such as function, homology or phenotype. Each HGNC gene family has its own dedicated gene family report on our website, www.genenames.org. We have recently redesigned these reports to support the visualisation and browsing of complex relationships between families and to provide extra curated information such as family descriptions, protein domain graphics and gene family aliases. Here, we review how our gene families are curated and explain how to view, search and download the gene family data.
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spelling pubmed-47390922016-02-04 A review of the new HGNC gene family resource Gray, Kristian A Seal, Ruth L Tweedie, Susan Wright, Mathew W Bruford, Elspeth A Hum Genomics Review The HUGO Gene Nomenclature Committee (HGNC) approves unique gene symbols and names for human loci. As well as naming genomic loci, we manually curate genes into family sets based on shared characteristics such as function, homology or phenotype. Each HGNC gene family has its own dedicated gene family report on our website, www.genenames.org. We have recently redesigned these reports to support the visualisation and browsing of complex relationships between families and to provide extra curated information such as family descriptions, protein domain graphics and gene family aliases. Here, we review how our gene families are curated and explain how to view, search and download the gene family data. BioMed Central 2016-02-03 /pmc/articles/PMC4739092/ /pubmed/26842383 http://dx.doi.org/10.1186/s40246-016-0062-6 Text en © Gray et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Gray, Kristian A
Seal, Ruth L
Tweedie, Susan
Wright, Mathew W
Bruford, Elspeth A
A review of the new HGNC gene family resource
title A review of the new HGNC gene family resource
title_full A review of the new HGNC gene family resource
title_fullStr A review of the new HGNC gene family resource
title_full_unstemmed A review of the new HGNC gene family resource
title_short A review of the new HGNC gene family resource
title_sort review of the new hgnc gene family resource
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739092/
https://www.ncbi.nlm.nih.gov/pubmed/26842383
http://dx.doi.org/10.1186/s40246-016-0062-6
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