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Measure transcript integrity using RNA-seq data
BACKGROUND: Stored biological samples with pathology information and medical records are invaluable resources for translational medical research. However, RNAs extracted from the archived clinical tissues are often substantially degraded. RNA degradation distorts the RNA-seq read coverage in a gene-...
Autores principales: | Wang, Liguo, Nie, Jinfu, Sicotte, Hugues, Li, Ying, Eckel-Passow, Jeanette E., Dasari, Surendra, Vedell, Peter T., Barman, Poulami, Wang, Liewei, Weinshiboum, Richard, Jen, Jin, Huang, Haojie, Kohli, Manish, Kocher, Jean-Pierre A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739097/ https://www.ncbi.nlm.nih.gov/pubmed/26842848 http://dx.doi.org/10.1186/s12859-016-0922-z |
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