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Measure transcript integrity using RNA-seq data

BACKGROUND: Stored biological samples with pathology information and medical records are invaluable resources for translational medical research. However, RNAs extracted from the archived clinical tissues are often substantially degraded. RNA degradation distorts the RNA-seq read coverage in a gene-...

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Detalles Bibliográficos
Autores principales: Wang, Liguo, Nie, Jinfu, Sicotte, Hugues, Li, Ying, Eckel-Passow, Jeanette E., Dasari, Surendra, Vedell, Peter T., Barman, Poulami, Wang, Liewei, Weinshiboum, Richard, Jen, Jin, Huang, Haojie, Kohli, Manish, Kocher, Jean-Pierre A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739097/
https://www.ncbi.nlm.nih.gov/pubmed/26842848
http://dx.doi.org/10.1186/s12859-016-0922-z

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