Cargando…
Hepatitis A seroprevalence in patients with chronic viral hepatitis in Konya, Turkey
AIM: Hepatitis A is among the diseases that can be prevented with vaccination in our time. Acute hepatitis A progresses more severely in individuals with a liver disease. Therefore, patients with a chronic liver disease (because of hepatitis B or hepatitis C) are advised vaccination with the hepatit...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams And Wilkins
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739311/ https://www.ncbi.nlm.nih.gov/pubmed/26703930 http://dx.doi.org/10.1097/MEG.0000000000000547 |
_version_ | 1782413723641577472 |
---|---|
author | Özden, Hale T. |
author_facet | Özden, Hale T. |
author_sort | Özden, Hale T. |
collection | PubMed |
description | AIM: Hepatitis A is among the diseases that can be prevented with vaccination in our time. Acute hepatitis A progresses more severely in individuals with a liver disease. Therefore, patients with a chronic liver disease (because of hepatitis B or hepatitis C) are advised vaccination with the hepatitis A vaccine. This study is aimed to determine the seroprevalence of hepatitis A virus (HAV) antibodies in patients infected with hepatitis C virus or hepatitis B virus in Konya province of Turkey. METHODS: A total of 537 patients who had chronic viral hepatitis between January 2011 and December 2014 were included in the study. Serum samples were collected from each patient and tested for anti-HAV using the chemiluminescent microparticle immunoassay. RESULTS: The overall seroprevalence of total anti-HAV IgG was 94.2%. The overall prevalence of anti-HAV IgG in patients with chronic hepatitis B virus and hepatitis C virus infection was 97.5 and 93.6%, respectively. Anti-HAV IgG positivity was 97.4% in cirrhotic patients and 93.9% in noncirrhotic individuals. CONCLUSION: At the end of the study, being older than 40 years and living in a rural area were found to be independent risk factors for anti-HAV IgG seropositivity. In conclusion, we recommend that patients younger than 40 years and/or those living in cities and having a chronic liver disease should be vaccinated with the hepatitis A vaccine. |
format | Online Article Text |
id | pubmed-4739311 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Lippincott Williams And Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-47393112016-02-17 Hepatitis A seroprevalence in patients with chronic viral hepatitis in Konya, Turkey Özden, Hale T. Eur J Gastroenterol Hepatol Original Articles: Hepatitis AIM: Hepatitis A is among the diseases that can be prevented with vaccination in our time. Acute hepatitis A progresses more severely in individuals with a liver disease. Therefore, patients with a chronic liver disease (because of hepatitis B or hepatitis C) are advised vaccination with the hepatitis A vaccine. This study is aimed to determine the seroprevalence of hepatitis A virus (HAV) antibodies in patients infected with hepatitis C virus or hepatitis B virus in Konya province of Turkey. METHODS: A total of 537 patients who had chronic viral hepatitis between January 2011 and December 2014 were included in the study. Serum samples were collected from each patient and tested for anti-HAV using the chemiluminescent microparticle immunoassay. RESULTS: The overall seroprevalence of total anti-HAV IgG was 94.2%. The overall prevalence of anti-HAV IgG in patients with chronic hepatitis B virus and hepatitis C virus infection was 97.5 and 93.6%, respectively. Anti-HAV IgG positivity was 97.4% in cirrhotic patients and 93.9% in noncirrhotic individuals. CONCLUSION: At the end of the study, being older than 40 years and living in a rural area were found to be independent risk factors for anti-HAV IgG seropositivity. In conclusion, we recommend that patients younger than 40 years and/or those living in cities and having a chronic liver disease should be vaccinated with the hepatitis A vaccine. Lippincott Williams And Wilkins 2016-03 2016-01-01 /pmc/articles/PMC4739311/ /pubmed/26703930 http://dx.doi.org/10.1097/MEG.0000000000000547 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Original Articles: Hepatitis Özden, Hale T. Hepatitis A seroprevalence in patients with chronic viral hepatitis in Konya, Turkey |
title | Hepatitis A seroprevalence in patients with chronic viral hepatitis in Konya, Turkey |
title_full | Hepatitis A seroprevalence in patients with chronic viral hepatitis in Konya, Turkey |
title_fullStr | Hepatitis A seroprevalence in patients with chronic viral hepatitis in Konya, Turkey |
title_full_unstemmed | Hepatitis A seroprevalence in patients with chronic viral hepatitis in Konya, Turkey |
title_short | Hepatitis A seroprevalence in patients with chronic viral hepatitis in Konya, Turkey |
title_sort | hepatitis a seroprevalence in patients with chronic viral hepatitis in konya, turkey |
topic | Original Articles: Hepatitis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739311/ https://www.ncbi.nlm.nih.gov/pubmed/26703930 http://dx.doi.org/10.1097/MEG.0000000000000547 |
work_keys_str_mv | AT ozdenhalet hepatitisaseroprevalenceinpatientswithchronicviralhepatitisinkonyaturkey |