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ADAMTS-18 in the host tissues exerts little effect on breast tumor progress in a murine 4T1 breast cancer model
BACKGROUND: In this study, we aimed to identify a novel extracellular proteinase ADAMTS-18 that could be a potential tumor suppressor gene. RESULTS: We successfully constructed Adamts-18 knockout mice with BALB / c background. RT-PCR analysis showed syngeneic mammary tumor cell line 4 T1 per se has...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739331/ https://www.ncbi.nlm.nih.gov/pubmed/26841794 http://dx.doi.org/10.1186/s12952-016-0045-0 |