In Vitro Determination of Respimat(®) Dose Delivery in Children: An Evaluation Based on Inhalation Flow Profiles and Mouth–Throat Models

Background: Aerosol therapy in young children can be difficult. A realistic model based on handling studies and in vitro investigations can complement clinical deposition studies and be used to enable dose-to-the-lung (DTL) predictions. Methods: Predictions on dose delivery to the lung were based on...

Descripción completa

Detalles Bibliográficos
Autores principales: Bickmann, Deborah, Kamin, Wolfgang, Sharma, Ashish, Wachtel, Herbert, Moroni-Zentgraf, Petra, Zielen, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739345/
https://www.ncbi.nlm.nih.gov/pubmed/26098994
http://dx.doi.org/10.1089/jamp.2014.1166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739345/
https://www.ncbi.nlm.nih.gov/pubmed/26098994
http://dx.doi.org/10.1089/jamp.2014.1166

Ejemplares similares