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In Vitro Determination of Respimat(®) Dose Delivery in Children: An Evaluation Based on Inhalation Flow Profiles and Mouth–Throat Models
Background: Aerosol therapy in young children can be difficult. A realistic model based on handling studies and in vitro investigations can complement clinical deposition studies and be used to enable dose-to-the-lung (DTL) predictions. Methods: Predictions on dose delivery to the lung were based on...
Autores principales: | Bickmann, Deborah, Kamin, Wolfgang, Sharma, Ashish, Wachtel, Herbert, Moroni-Zentgraf, Petra, Zielen, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739345/ https://www.ncbi.nlm.nih.gov/pubmed/26098994 http://dx.doi.org/10.1089/jamp.2014.1166 |
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