Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids

Tacrolimus and sirolimus are important immunosuppressive drugs used in human islet transplantation; however, they are linked to detrimental effects on islets and reduction of long-term graft function. Few studies investigate the direct effects of these drugs combined in parallel with single drug exp...

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Detalles Bibliográficos
Autores principales: Kloster-Jensen, Kristine, Sahraoui, Afaf, Vethe, Nils Tore, Korsgren, Olle, Bergan, Stein, Foss, Aksel, Scholz, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739465/
https://www.ncbi.nlm.nih.gov/pubmed/26885529
http://dx.doi.org/10.1155/2016/4196460

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