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The Effects of Lung Protective Ventilation or Hypercapnic Acidosis on Gas Exchange and Lung Injury in Surfactant Deficient Rabbits

BACKGROUND: Permissive hypercapnia has been shown to reduce lung injury in subjects with surfactant deficiency. Experimental studies suggest that hypercapnic acidosis by itself rather than decreased tidal volume may be a key protective factor. OBJECTIVES: To study the differential effects of a lung...

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Detalles Bibliográficos
Autores principales: Hummler, Helmut D., Banke, Katharina, Wolfson, Marla R., Buonocore, Giuseppe, Ebsen, Michael, Bernhard, Wolfgang, Tsikas, Dimitrios, Fuchs, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739580/
https://www.ncbi.nlm.nih.gov/pubmed/26840779
http://dx.doi.org/10.1371/journal.pone.0147807