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Flavonoid Compound Icariin Activates Hypoxia Inducible Factor-1α in Chondrocytes and Promotes Articular Cartilage Repair

Articular cartilage has poor capability for repair following trauma or degenerative pathology due to avascular property, low cell density and migratory ability. Discovery of novel therapeutic approaches for articular cartilage repair remains a significant clinical need. Hypoxia is a hallmark for car...

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Detalles Bibliográficos
Autores principales: Wang, Pengzhen, Zhang, Fengjie, He, Qiling, Wang, Jianqi, Shiu, Hoi Ting, Shu, Yinglan, Tsang, Wing Pui, Liang, Shuang, Zhao, Kai, Wan, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739592/
https://www.ncbi.nlm.nih.gov/pubmed/26841115
http://dx.doi.org/10.1371/journal.pone.0148372

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