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Regulation of Nuclear Receptor Nur77 by miR-124
The nuclear receptor Nur77 is commonly upregulated in adult cancers and has oncogenic functions. Nur77 is an immediate-early response gene that acts as a transcription factor to promote proliferation and protect cells from apoptosis. Conversely, Nur77 can translocate to the mitochondria and induce a...
Autores principales: | Tenga, Alexa, Beard, Jordan A., Takwi, Apana, Wang, Yue-Ming, Chen, Taosheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739595/ https://www.ncbi.nlm.nih.gov/pubmed/26840408 http://dx.doi.org/10.1371/journal.pone.0148433 |
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