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Vaccination with an Attenuated Mutant of Ehrlichia chaffeensis Induces Pathogen-Specific CD4(+) T Cell Immunity and Protection from Tick-Transmitted Wild-Type Challenge in the Canine Host
Ehrlichia chaffeensis is a tick-borne rickettsial pathogen and the causative agent of human monocytic ehrlichiosis. Transmitted by the Amblyomma americanum tick, E. chaffeensis also causes disease in several other vertebrate species including white-tailed deer and dogs. We have recently described th...
Autores principales: | McGill, Jodi L., Nair, Arathy D. S., Cheng, Chuanmin, Rusk, Rachel A., Jaworski, Deborah C., Ganta, Roman R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739596/ https://www.ncbi.nlm.nih.gov/pubmed/26841025 http://dx.doi.org/10.1371/journal.pone.0148229 |
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